Radiotherapy and radiosurgery for benign skull base meningiomas

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Radiotherapy and radiosurgery for benign skull base meningiomas

Meningiomas located in the region of the base of skull are difficult to access. Complex combined surgical approaches are more likely to achieve complete tumor removal, but frequently at a cost of treatment related high morbidity. Local control following subtotal excision of benign meningiomas can be improved with conventional fractionated external beam radiation therapy with a reported 5-year p...

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Fractionated stereotactic conformal radiotherapy for large benign skull base meningiomas

PURPOSE To assess the safety and efficacy of fractionated stereotactic radiotherapy (FSRT) for large skull base meningiomas. METHODS AND MATERIALS Fifty-two patients with large skull base meningiomas aged 34-74 years (median age 56 years) were treated with FSRT between June 2004 and August 2009. All patients received FSRT for residual or progressive meningiomas more than 4 centimeters in grea...

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Long term experience of gamma knife radiosurgery for benign skull base meningiomas.

OBJECTIVES As most reports on the gamma knife have related only to short or mid-term results, we decided to evaluate the effectiveness and toxicity of radiosurgical treatment for benign skull base meningiomas in 200 patients with a follow up of 5-12 years to define the role of gamma knife radiosurgery (GKRS) for basal meningiomas and to provide further data for comparison with other treatment o...

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Long-term outcomes of fractionated stereotactic radiotherapy for intracranial skull base benign meningiomas in single institution.

OBJECTIVE To investigate the outcome of linac-based fractionated stereotactic radiotherapy over the last 10 years for intracranial skull base benign meningiomas in patients who were inoperable, who had residual tumors with some components of high mitotic index after surgery and who experienced relapse of the tumor. METHODS Twenty-seven patients with intracranial skull base benign meningiomas ...

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short term outcomes of gamma knife radiosurgery for skull base meningiomas in iran

introduction: skull base meningiomas constitute a large proportion of the meningiomas, which are the most common benign brain tumors. the treatment of skull base meningiomas is specially challenging and controversial due to the proximity of these tumors to the vital brain structures. radiosurgery is now emerging as an efficient alternative treatment modality which involves the ablation of tumor...

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ژورنال

عنوان ژورنال: Radiation Oncology

سال: 2009

ISSN: 1748-717X

DOI: 10.1186/1748-717x-4-42